女性腰圍粗或與乳腺癌相關大綱

You may have heard that the ratio of your waist to hip measurement is important to your life expectancy. In fact it's thought to be more significant than your BMI .

你可能聽別人說過：腰圍和臀圍的比例對你的壽命至關重要。事實上，這一比例遠比你的身體質量指數重要。

If the ratio comes out at less than one - which it would if your waist measures, say, 36ins and your hips 44ins - then your chances of a long life are good. If, however, the ratio is greater than one (say, waist 50ins, hips 46ins) the outlook isn't so good.

如果比例小於1--比如當你的腰圍是36英寸，而你的臀圍是44英寸時--那你就很有可能長壽。然而，如果比例大於1（比如腰圍50英寸，臀圍46英寸），那前景就不那麼樂觀了。

And now scientists have found this all important ratio is tied to the risk of a deadly form of breast cancer. This is because fat round the waist, giving you an "apple shape", is itself more deadly than fat elsewhere.

現在，科學家發現這一重要的比例與一種致命的乳腺癌風險相關。這是因爲腰部的脂肪，讓你呈現"蘋果狀"，本身就比身體其它部位的脂肪更致命。

The new research from Shandong University in China shows that "pear shaped" women who have fat on their thighs, hips and buttocks are prone to a more treatable form of breast cancer. They discovered that women with a higher BMI but with a waist-to-hip ratio of less than one are more likely to have ER+ (oestrogen-receptor positive) breast cancer.

中國山東大學的新研究表明："梨狀"女性（大腿和臀部有脂肪）更容易患有可以治癒的乳腺癌。他們發現：身體質量指數高但腰圍與臀部比小於1的女性更有可能患雌激素受體陽性乳腺癌。

This form of the disease, in which oestrogen can attach itself to proteins in the cancer and stimulate growth, is usually treated with hormone blocking drugs. In contrast, women with a high waist-to-hip ratio are more likely to have ER- (oestrogen-receptor negative) breast cancer.

這種疾病的雌激素自行與癌症中的蛋白質結合、刺激生長，通常可用激素阻斷藥物進行治療。反過來，腰臀比較高的女性更有可能患有雌激素受體陰性乳腺癌。

This form of the disease can't be treated with hormone blocking drugs and chemotherapy has to be employed.

這類疾病無法用激素阻斷藥物進行治療，必須採用化療。

Significantly, the greater risk of developing ER-breast cancer in women with a high waist-to-hip ratio is present even if they aren't obese, the research found. For the study, researchers recruited 1,316 women newly diagnosed with breast cancer. Body measurements were taken, details of their form of cancer noted (whether it was ER+ or ER-) and they were compared to a control group.

值得注意的是，研究發現：即使腰臀比高的女性並不胖，她們還是更有可能患有雌激素受體陰性乳腺癌。研究人員招募了1316位剛診斷出患有乳腺癌的女性，對她們進行了身體檢查，記錄其癌症類型的細節（無論是雌激素受體陽性乳腺癌還是雌激素受體陰性乳腺癌），並將其與對照組對比。

Lead researcher Dr Zhigang Yu said: "A possible reason is that subcutaneous fat is involved in oestrogen production, which may promote ER+ breast cancer. Visceral or belly fat is more closely related to insulin resistance and may be more likely to promote ER- breast cancer."

首席研究員餘之剛說："一個可能的原因就是皮下脂肪參與了雌激素的生成，這可能會促進雌激素受體陽性乳腺癌。內臟或腹部脂肪與胰島素抵抗密切相關，這更有可能促進雌激素受體陰性乳腺癌。"