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50歲後減肥或降低患乳腺癌的風險

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Losing Weight After Age 50 May Reduce Breast Cancer Risk

50歲後減肥或降低患乳腺癌的風險

Doctors who say weight loss can reduce the risk for breast cancer finally have some pretty solid science on their side: A study published Tuesday in the JNCI: Journal of the National Cancer Institute found that postmenopausal women may decrease their likelihood of getting breast cancer if they lose weight––even a small amount.

那些聲稱減肥可以降低患乳腺癌風險的醫生終於得到了有力的科學支持:週二發表在《國家癌症研究所雜誌》上的一篇研究發現,減肥有助降低絕經女性患乳腺癌的風險,即便只減一兩斤

50歲後減肥或降低患乳腺癌的風險

"Excess body weight is a known cause of postmenopausal breast cancer," study author Lauren Teras, PhD, scientific director for epidemiology research at the American Cancer Society, tells Health. "An important question is, can you reverse it? Believe it or not, this was not something we knew for certain."

“體重過重是絕經後女性患乳腺癌的已知原因,”研究作者及美國癌症學會流行病學研究的科學主任勞倫·泰拉斯(Lauren Teras)博士對《健康》期刊說道:“重要的是,這個過程可逆嗎?信不信由你,但我們並不確定。”

Until now, that is. The researchers analyzed data from 10 separate prospective studies, involving 180,000 women over age 50 who were tracked for a decade. Nearly 7,000 of the women received a breast cancer diagnosis during that time, according to the data.

這就是目前的現狀。研究員分析了10項不同的前瞻性研究的數據,這些數據涉及18萬名50歲以上的女性,研究員對她們跟蹤研究了10年。數據顯示,在此期間,近7000名婦女被診斷出患有乳腺癌。

Compared to postmenopausal women who maintained a stable weight over approximately 10 years, the researchers found that women who lost weight—even as little as 4.5 pounds—had a 13 percent lower risk of developing breast cancer. And more weight lost led to an even greater impact on cancer risk—at 20 pounds of sustained weight loss, women cut their risk of breast cancer by about 25%, Teras told NBC News. (The researchers accounted for other risk factors that can impact obesity and/or breast cancer risk, like physical activity levels and whether the women were on hormone replacement therapy.)

研究員發現在這10年內,與體重基本保持穩定的絕經女性相比,減肥的女性(即便只減了4.5磅)患乳腺癌的風險降低了13%。而減重更多對患癌率的影響也更大——減肥20磅左右的女性患乳腺癌的風險降低了25%,泰拉斯對《美國全國廣播公司新聞》說道。(研究員表示其它因素也可能影響肥胖和/或乳腺癌風險,例如女性的鍛鍊水平以及是否接受激素替代治療。)

"This is particularly important for the 40 percent of women worldwide, who are overweight or obese and therefore at higher risk for breast cancer," says Teras. "Given that breast cancer is the most commonly diagnosed cancer in women, the question of whether weight loss can reduce breast cancer risk is of great public health importance."

“這一點對於全球40%的超重或肥胖女性至關重要,因爲這些人羣患乳腺癌的風險更高,”泰拉斯說道。“鑑於乳腺癌是女性最常見的癌症,減肥是否可以降低患乳腺癌的風險具有重大的公共衛生意義。”

Although the study was restricted to women aged 50 years and older, Teras stresses that it is important for women of all ages to maintain a healthy body weight to avoid a variety of negative health outcomes.

儘管這項研究的受試者僅限於50歲及以上的女性,但泰拉斯強調,對於所有年齡段的女性而言,保持健康的體重對避免各種負面的健康後果至關重要。