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哪些人不能每天服用阿司匹林

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Many healthy people take a daily aspirin to reduce the risk of heart disease and stroke, but a new study has found that more than 11 percent of them should not be doing so.

爲了降低心臟病和中風的風險,許多健康的人也每天服用阿司匹林,但一項新的研究發現,在這些人當中,有11%以上其實不應這樣做。

Aspirin has well established benefits, but also carries the risk of gastrointestinal bleeding. The American Heart Association guidelines recommend daily aspirin for primary prevention in people with a 10-year cardiovascular risk of 10 percent or more. Other guidelines suggest the cut-off should be a risk of 6 percent. (You can assess your risk at the National Institutes of Health’s online risk calculator.)

雖然阿司匹林的健康效益久已確立,但它也會帶來胃腸道出血的風險。美國心臟協會(American Heart Association)的指南建議,心血管疾病10年風險達到10%或以上者可每天服用阿司匹林作爲一級預防。其他指南則建議風險cut-off值(即截止值)應爲6%(你可以使用美國國立衛生研究院[National Institutes of Health]的在線風險計算器來評估自己的風險)。

哪些人不能每天服用阿司匹林

Researchers studied records of 68,808 patients taking aspirin for primary cardiovascular prevention in various kinds of medical practices between 2008 and 2011. They found that 7,972 of them, or 11.6 percent, were taking aspirin daily despite having a cardiovascular disease risk of less than 6 percent.

研究人員研究了2008年至2011年間,多種不同的醫療診所中,服用阿司匹林作爲心血管疾病一級預防的68808名患者的醫療記錄。他們發現,其中7972人(11.6%)的心血管疾病風險低於6%,但他們仍每日服用阿司匹林。

In some groups, inappropriate use was even more common. For example, 17 percent of women taking aspirin had less than a 6 percent risk. The study was published in The Journal of the American College of Cardiology.

阿司匹林使用不當的情況在某些人羣中還要更爲普遍。例如,在服用阿司匹林的女性中,有17%的人心血管疾病風險都小於6%。這項研究發表在《美國心臟病學會雜誌》(The Journal of the American College of Cardiology)上。

“We need a discussion between the patient and the clinician to see that we’re not causing more harm than good,” said the senior author, Dr. Salim S. Virani, a cardiologist at Baylor College of Medicine. Because a lot of patients take aspirin, he added, the “public health risk could be high.”

該研究的責任作者,美國貝勒醫學院(Baylor College of Medicine)的心臟病學家薩利姆·S·韋拉尼(Dr. Salim S. Virani)認爲:“患者和醫生需要討論一下這樣做是不是弊大於利。”由於有很多患者服用阿司匹林,他補充道,“公共衛生風險可能會非常高。”