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美國出現抵抗終極抗生素的感染病例

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BBC News -The first case of an infection that resists the antibiotic of last resort - colistin - has been detected in the US. The 48-year old woman from Pennsylvania recovered and the infection was vulnerable to other antibiotics.

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BBC新聞 - 抵抗抗生素的最後防線 - 粘菌素 - 的首例感染在美國發現。賓州48歲的女病人已康復,感染對其它抗生素有反應。

However, colistin is hugely symbolic as it is used when other drugs fail and officials warned the world was now reaching "the end of the road" for antibiotics.

然而,粘菌素有巨大象徵意義,因爲它是在其它藥物無效時才使用的,衛生官員警告,世界現正走向抗生素的"末路"。

Colistin resistance was first discovered in China at the end of 2015. The study sparked concern around the world, and intensive testing rapidly discovered bugs that can resist colistin in Europe and Asia.

粘菌素抵抗2015年末首次在中國發現。相關研究引發全世界的擔憂,隨後的密集試驗迅速在歐洲和亞洲發現了能夠抵抗粘菌素的細菌。

Now data from the US has identified the first case in a patient, who had a urinary-tract infection, as well as colistin-resistant bacteria in farm animals and meat on supermarket shelves.

現在,來自美國的數據顯示,一名尿路感染病人身上出現首例粘菌素抵抗,農場牲畜和超市貨架的肉類上也發現了對粘菌素產生耐藥性的細菌。

It is not clear where the infection came from as the patient had not travelled recently and colistin is not widely used in the US.

尚不清楚感染從何而來,因爲病人近期沒有出行,且粘菌素在美國並未廣泛使用。

The DNA that gives bacteria resistance to colistin - the mcr-1 gene - can spread rapidly between species. The concern is that colistin resistance will now hook-up with other forms of antibiotic resistance to create infections that cannot be treated.

使細菌對粘菌素產生耐藥性的DNA - mcr-1基因 - 可在物種間迅速傳播。令人擔憂的是,粘菌素抵抗現在將會與其它形式的抗生素抵抗勾搭,造成無法醫治的感染。

Thomas Frieden, the director of the Centers for Disease Control and Prevention, said: "The more we look at drug resistance, the more concerned we are…The medicine cabinet is empty for some patients, it is the end of the road for antibiotics unless we act urgently."

美國疾控中心主任弗利登說:"我們對耐藥性研究得越多,就越擔憂……對某些病人,藥箱已空,無藥可用了, 抗生素走到了末路,除非我們緊急行動起來。"

However, Dr Beth Bell, also from the CDC, said in an interview: "Luckily haven't seen actual bacteria that are resistant to every single antibiotic."

但同樣來自疾控中心的貝爾博士接受採訪時說:"幸運的是,還沒有見過目前存在對每一種抗生素都有耐藥性的細菌。"