咖啡與甲狀腺藥物同時服用產生的問題

Around the world, many people start their day with a cup of coffee, a cappuccino, or an espresso. At the same time, there are many people with various thyroid conditions who rely on synthetic thyroid hormone replacement medication like levothyroxine (i.e., Synthroid) to treat their hypothyroidism. And following doctor's instructions, most of those people take their thyroid pills in the morning.

在世界各地,很多人都以一杯咖啡、卡布奇諾或濃縮咖啡開始他們的一天，與此同時,有很多依靠合成甲狀腺激素替代藥物如左旋甲狀腺素來治療甲狀腺衰退的不同甲狀腺狀況的人 (例如左甲狀腺素)。遵照醫囑,大部分的人都在早上服用甲狀腺藥物。

There is a problem, however, when coffee drinkers take their prescription thyroid medication along with their morning coffee or espresso. Several studies have found that having coffee or espresso at the same time—or shortly after—taking levothyroxine tablets can significantly lower the absorption of the thyroid medication.

然而當喝咖啡的人，早上同時服用處方甲狀腺藥物時，這就是一個問題。幾項研究已經發現,同時喝咖啡或濃咖啡-或稍後飲用左甲狀腺素藥片的，可以顯著降低甲狀腺藥物的吸收。

In one study published in the journal Thyroid, researchers found the rise of T4—a reflection of absorption of the medication—reduced by 25 percent, and they even noticed drops by as much as 57 percent in other patients in the study. Overall, theThyroid journal study showed that the reduction typically ranged from 23 percent to as much as 55 percent.

發表在《甲狀腺》雜誌的一項研究中，研究人員發現T4升高-一種藥物吸收反應-藥物吸收會減少25%,甚至他們注意到其他病人藥物吸收率會下降多達57%。總的來說,《甲狀腺》雜誌研究表明藥物吸收的減少通常從23%到55%不等。

Consistently, researchers have found that for patients taking levothyroxine tablets, absorption is affected by drinking coffee and espresso within an hour of taking the thyroid drugs. The ability to reach targeted thyroid levels is impaired if a thyroid patient does not wait 60 minutes after taking the levothyroxine before drinking coffee or espresso.

研究人員一致認爲,服用左旋甲狀腺素片的病人, 服用甲狀腺藥物一小時內飲用咖啡和濃縮咖啡，會影響藥物吸收。如果甲狀腺病人在喝咖啡或濃咖啡之後沒有等60分鐘，就服用左旋甲狀腺素片，達到預期甲狀腺水平的能力會受影響。