研究發現:大豆蛋白或能緩解炎症性腸道疾病病情
A diet supplemented with soy protein may ease the severity of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis, according to American research carried out on mice and cultured human colon cells. The news comes ahead of World Inflammatory Bowel Disease Day, May 19.
據美國開展的一項基於老鼠和人工培養的人類結腸細胞的研究表示：一份補充大豆蛋白的飲食或能緩解炎症性腸道疾病病情，比如克羅恩病和潰瘍性結腸炎。這一消息發生在5月19日世界炎症性腸道疾病日之前。Researchers at Penn State University in the USA found that soy protein concentrate had an antioxidant and cytoprotective effect in cultured human bowel cells and moderated the severity of inflammation in mice with induced inflammatory bowel disease.
美國賓夕法尼亞州立大學的研究人員發現：大豆蛋白濃縮物在人工培養的人腸細胞中含一種抗氧化劑，並有保護細胞的作用，能緩和患有炎症性腸道疾病的小鼠的炎症程度。Crohn's disease and ulcerative colitis are two forms of inflammatory bowel disease (IBD), characterized by chronic inflammation of all or part of the digestive tract, generally the intestine, the colon and the rectum. Symptoms include abdominal pain, diarrhea, fatigue, appetite loss and weight loss.
克羅恩病和潰瘍性結腸炎是兩種不同的炎症性腸道疾病，其特徵是全部或部分消化道，通常爲腸、結腸和直腸的慢性炎症。症狀包括腹痛、腹瀉、疲勞、沒胃口和體重下降。
Mice with an induced condition similar to ulcerative colitis were given a dietary soy protein concentrate (12%). An equivalent amount of other forms of protein was removed from their diet to replicate a more human-relevant scenario. Both body weight loss and swelling of the spleen improved in the mice. What's more, the scientists observed reduced inflammation in the colon and improved gut barrier function.
研究員給患有類似於潰瘍性結腸炎的老鼠提供了大豆蛋白濃縮物（12%濃度）飲食。同時不再提供等量的其它形式的蛋白，以複製更人性化的場景。老鼠的體重下降和脾臟腫脹症狀均有改善。此外，科學家們還觀察到了結腸炎症有所減輕，腸屏障功能也有所改善。
The researchers consider that the inflammation-moderating effects may be linked to soy protein, but not solely. In fact, the soy protein concentrate contains 70% protein as well as some soy fiber, which could also have a beneficial effect on the digestive system. The scientists plan further studies to investigate.
研究員認爲炎症緩解可能與大豆蛋白有關，但卻不限於此。事實上，大豆蛋白濃縮物含有70%的蛋白及一些大豆纖維，有益於消化系統。科學家計劃進一步研究調查。Four million people worldwide suffer from IBD. Both Crohn's disease and ulcerative colitis are treated with anti-inflammatory or immunomodulatory therapies or by surgery in severe cases. World Inflammatory Bowel Disease Day is May 19, 2017. The study is published in the Journal of Nutritional Biochemistry.
全世界有400萬人患有炎症性腸道疾病。人們通常用抗炎或免疫調節療法治療克羅恩病和潰瘍性結腸炎，嚴重情況下，還會動手術。2017年世界炎症性腸道疾病日爲5月19日。該研究發表在《營養生物化學》期刊上（the Journal of Nutritional Biochemistry）。
